FIELD: biotechnology.
SUBSTANCE: compositions and methods for the treatment of ophthalmic disorders in a subject are described. A vector based on an adeno associated virus that includes a nucleic acid molecule containing a sequence that encodes CNGA3, a vector based on an adeno associated virus that includes a nucleic acid molecule containing a sequence that encodes CNGB3, and a vector based on an adeno associated virus that includes a nucleic acid molecule containing a sequence that encodes REP-1 are also described.
EFFECT: invention expands the arsenal of means for the treatment of ophthalmic diseases.
39 cl, 12 dwg, 23 tbl, 7 ex
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