FIELD: medicine.
SUBSTANCE: compositions for the treatment of Alzheimer’s disease are proposed, containing at least one AAV vector. A method for the treatment of Alzheimer’s disease is proposed, including the intrathecal delivery to a patient of one of the above-mentioned compositions, in which biomass of at least one vector expresses immunoglobulin, specific to Aβ, beta-secretase and/or tau protein.
EFFECT: proposed group of inventions provides for the effective treatment of Alzheimer’s disease.
11 cl, 1 dwg, 1 tbl, 3 ex
Title |
Year |
Author |
Number |
COMPOSITION AND METHOD FOR TREATING A COMPLEMENT-MEDIATED DISEASE |
2016 |
- Song, Wenchao
- Gullipalli, Damodar
- Miwa, Takashi
|
RU2727411C2 |
EXPRESSION OF ANTIGEN-BINDING PROTEINS IN NERVOUS SYSTEM |
2020 |
- Elmer, Bradford
- Yang, Zhi-Yong
- Nabel, Gary
|
RU2831086C2 |
COMPOSITIONS AND METHODS OF TREATING MPS1 |
2014 |
- Uilson Dzhejms M.
- Gurda Brittni L.
|
RU2708318C2 |
ENGINEERED ADENO-ASSOCIATED (AAV) VECTORS FOR TRANSGENE EXPRESSION |
2020 |
- Maguire, Casey A.
- Hudry, Eloise Marie
- Hanlon, Killian S.
|
RU2839774C2 |
THERAPEUTIC AGENTS AND METHODS FOR THE TREATMENT OF TLR2-MEDIATED DISEASES AND DISORDERS |
2019 |
- Witztum, Joseph, L.
- Tsimikas, Sotirios
- Que, Xuchu
|
RU2791022C2 |
MONOCLONAL ANTIBODIES AGAINST HUMAN TIM-3 |
2019 |
|
RU2777336C1 |
METHODS FOR TREATMENT OF DANON'S DISEASE AND OTHER AUTOPHAGY DISORDERS |
2017 |
- Adler, Eric, D.
- Nelson, Bradley
- Hashem, Sherin
|
RU2777571C2 |
TREATING CANCER USING CHIMERIC ANTIGEN-SPECIFIC RECEPTOR BASED ON HUMANIZED ANTI-EGFRvIII ANTIBODY |
2014 |
- Brogdon, Jennifer
- Johnson, Laura Alexandra
- June, Carl H.
- Loew, Andreas
- Maus, Marcela
- Scholler, John
- Okada, Hideho
|
RU2831418C2 |
OPTIMIZED CLN1 GENES AND EXPRESSION CASSETTES, AND THEIR APPLICATION |
2017 |
|
RU2764919C2 |
DNA ANTIBODY CONSTRUCTIONS FOR USE AGAINST LYME DISEASE |
2017 |
- Weiner, David, B.
- Flingai, Seleeke
|
RU2813829C2 |