FIELD: medicine.
SUBSTANCE: compositions for the treatment of Alzheimer’s disease are proposed, containing at least one AAV vector. A method for the treatment of Alzheimer’s disease is proposed, including the intrathecal delivery to a patient of one of the above-mentioned compositions, in which biomass of at least one vector expresses immunoglobulin, specific to Aβ, beta-secretase and/or tau protein.
EFFECT: proposed group of inventions provides for the effective treatment of Alzheimer’s disease.
11 cl, 1 dwg, 1 tbl, 3 ex
| Title |
Year |
Author |
Number |
| COMPOSITION AND METHOD FOR TREATING A COMPLEMENT-MEDIATED DISEASE |
2016 |
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|
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2014 |
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|
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2019 |
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|
RU2791022C2 |
| MONOCLONAL ANTIBODIES AGAINST HUMAN TIM-3 |
2019 |
|
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| METHODS FOR TREATMENT OF DANON'S DISEASE AND OTHER AUTOPHAGY DISORDERS |
2017 |
- Adler, Eric, D.
- Nelson, Bradley
- Hashem, Sherin
|
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| OPTIMIZED CLN1 GENES AND EXPRESSION CASSETTES, AND THEIR APPLICATION |
2017 |
|
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2017 |
- Weiner, David, B.
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|
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| ANTI-C5 ANTIBODIES AND THEIR USE |
2018 |
- Song, Wenchao
- Sato, Sayaka
- Miwa, Takashi
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|
RU2774716C2 |
| MODIFIED CAPSID PROTEINS FOR IMPROVED DELIVERY OF PARVOVIRUS VECTORS |
2016 |
- Samulski, Richard Jude
- Warischalk, Jayme
|
RU2751953C2 |
| INTRATHECAL DELIVERY OF RECOMBINANT ADENO-ASSOCIATED VIRUS ENCODING METHYL-CPG-BINDING PROTEIN 2 |
2017 |
- Kaspar, Brian, K.
- Foust, Kevin
|
RU2788084C2 |
