APPLICATION OF AN EZH2 INHIBITOR IN COMBINATION WITH A BTK INHIBITOR IN PRODUCTION OF A MEDICINAL PRODUCT FOR TREATING A TUMOUR Russian patent published in 2021 - IPC A61K31/4545 A61K31/50 A61P35/00 C07D237/00 C07D405/14 

Abstract RU 2762893 C2

FIELD: medicine.

SUBSTANCE: invention relates to an application of a combination of an EZH2 inhibitor and a BTK inhibitor in production of a medicinal product for treating a tumour, differs in that the EZH2 inhibitor constitutes a compound by the formula (IE) or a pharmacologically acceptable salt thereof, the BTK inhibitor constitutes a compound by the formula (IIA) or a pharmacologically acceptable salt thereof, wherein the tumour is selected from the group consisting of diffuse B-large cell lymphoma and follicular lymphoma.

EFFECT: application of an EZH2 inhibitor and a BTK inhibitor in treatment of tumours.

7 cl, 5 dwg, 6 tbl, 4 ex

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RU 2 762 893 C2

Authors

Ma Ke

Tsao Gotsin

Yan Chanyun

Chzhan Lyanshan

Dates

2021-12-23Published

2018-05-17Filed