FIELD: pharmaceutics.
SUBSTANCE: invention relates to amide derivatives, which have blocking activity on voltage-gated sodium channels, such as Nav1.7 and Nav1.8, and can be used in treating or preventing disorders and diseases in which voltage-gated sodium channels are involved. Invention also relates to pharmaceutical compositions comprising said compounds, and to the use of said compounds and compositions in preventing or treating diseases in which voltage-gated sodium channels are involved.
EFFECT: disclosed are amide derivatives as blockers Nav1.7 and Nav1.8.
13 cl, 4 tbl, 155 ex
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