IX PADUA FACTOR ANTIBODIES Russian patent published in 2022 - IPC C07K16/34 C07K16/36 C12N5/10 C12N15/13 C12N15/63 G01N33/50 

FIELD: biotechnology.

SUBSTANCE: group of inventions is described, including an antibody or its antigen-binding fragment that binds IX Padua factor, polypeptide that binds IX Padua factor, a conjugate that binds IX Padua factor, containing the above-mentioned antibody or antigen-binding fragment, or polypeptide, nucleic acid, an expression vector, a host cell, a kit for the detection of IX Padua factor, a composition for the detection of IX Padua factor (options), use of antibodies or an antigen-binding fragment, polypeptide, a conjugate, nucleic acid, a vector, a host cell and a kit for the detection of IX Padua factor in a sample, and a method for the detection of IX Padua factor in a sample obtained from a subject. In one of embodiments, the antibody or its antigen-binding fragment contains an amino acid sequence SSYAIS (SEQ ID NO: 6); GIVPAFGTANYAQKFQG (SEQ ID NO: 7); SWGVISFAY (SEQ ID NO: 8); RASQDISSYLN (SEQ ID NO: 9); AASNLQS (SEQ ID NO: 10); and MQYDSLPFTF (SEQ ID NO: 11).

EFFECT: invention expands the arsenal of means for binding IX Padua factor.

49 cl, 32 dwg, 1 tbl, 5 ex