MULTI-SPECIFIC ANTIGEN-BINDING MOLECULE HAVING SUBSTITUTE FUNCTIONAL ACTIVITY OF BLOOD COAGULATING FACTOR VIII CO-FACTOR, AND PHARMACEUTICAL COMPOSITION CONTAINING SPECIFIED MOLECULE AS ACTIVE INGREDIENT Russian patent published in 2024 - IPC C07K16/36 C07K16/46 A61K39/395 A61P7/04 

Abstract RU 2812909 C2

FIELD: biotechnology.

SUBSTANCE: invention relates to a bispecific antibody having the substituting functional activity of blood coagulating factor VIII, a method of its production, as well as a pharmaceutical composition containing it. Also an isolated nucleic acid encoding the above antibody, as well as a vector and a cell containing it are disclosed.

EFFECT: invention is effective for use in the prevention and/or treatment of bleeding, a disease involving bleeding, or a disease caused by bleeding.

15 cl, 10 dwg, 8 tbl, 4 ex

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RU 2 812 909 C2

Authors

Teranishi Yuri

Kato Kazuki

Koga Hikaru

Igawa Tomoyuki

Yamaguchi Kazuki

Soeda Tetsuhiro

Dates

2024-02-05Published

2018-09-27Filed