FIELD: biochemistry; biotechnology.
SUBSTANCE: disclosed are a hydrogel precursor composition in the form of an unreacted powder, comprising a thrombin activating enzyme, a transglutaminase cross-linking factor XIII enzyme, structural compounds A or A and B, which are branched polyethylene glycol, each having a functional group; method of producing said composition; kit for producing a hydrogel, comprising a container filled with a hydrogel precursor composition, a container with a reaction buffer, and, if necessary, instructions for a user; method of producing a hydrogel by resuspension of the disclosed composition in a reaction buffer, preferably containing calcium ions.
EFFECT: inventions provide reproducibility of hydrogels obtained from a hydrogel precursor composition and improvement of their consumer properties.
13 cl, 7 dwg, 1 tbl
| Title | Year | Author | Number |
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| PHARMACEUTICAL COMPOSITION COMPRISING FACTOR VIIA AND FACTOR XIII | 2001 |
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