FIELD: pharmacy.
SUBSTANCE: present invention relates to the field of pharmacy, namely to a method for producing a pastille dosed form. The pastille dosed form contains: a part of a disintegrating tablet; and a part of a lollipop shell containing a reservoir that holds the quickly disintegrating part. In this case, the part of the disintegrating tablet contains at least one pharmaceutically active ingredient. The method includes: manufacture of the part of the lollipop shell for one stage and provision for it of the possibility of cooling to an ambient temperature; creation of a deformable core or a tablet containing the disintegrating part of the tablet; addition of the deformable core or the tablet to the part of the lollipop shell; and use of minor push to the deformable core or the tablet to fill a pre-determined space within the part of the lollipop shell; and on-site sealing.
EFFECT: providing an effective method for producing a two-component dosed form, which is easily adapted to commercial production.
6 cl, 8 dwg, 9 tbl, 10 ex
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Authors
Dates
2022-05-12—Published
2018-01-25—Filed