FIELD: pharmaceuticals.
SUBSTANCE: group of inventions relates to treatment of cancer. The pharmaceutical composition for treating cancer includes 150 mg/ml anti-PD-1 antibody; 20 mM histidine buffer; 84 mg/ml trehalose; 0.2 mg/ml PS80 and 0.045 or 0.05 mg/ml EDTA, wherein said pharmaceutical composition has a pH of 5.0 +/- 0.5 . Also disclosed is another variant of implementation of the pharmaceutical composition.
EFFECT: composition with a high concentration of the antibody and reduced viscosity.
28 cl, 7 dwg, 26 tbl, 6 ex
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Authors
Dates
2022-05-25—Published
2019-03-04—Filed