FIELD: biotechnology.
SUBSTANCE: invention relates to the field of biotechnology, namely to the production of a humanized protein specifically binding human glycoprotein VI (hGPVI); it can be used in medicine. The produced protein is an antigen-binding fragment of an antibody, where a variable region of a heavy chain contains an amino acid sequence SEQ ID NO:7, and a variable region of a light chain contains a sequence SEQ ID NO:8 or SEQ ID NO:9.
EFFECT: produced protein can be used for the treatment of a cardiovascular disease or event associated with thrombosis.
9 cl, 14 dwg, 1 tbl, 5 ex
| Title | Year | Author | Number |
|---|---|---|---|
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