DRUG WITH A HYPOGLYCEMIC EFFECT AND A METHOD FOR OBTAINING IT Russian patent published in 2022 - IPC A61K36/28 A61K36/533 A61K36/45 A61K36/73 A61P3/10 

Abstract RU 2773856 C1

FIELD: pharmaceutics.

SUBSTANCE: claimed group of inventions relates to the pharmaceutical industry, namely to a drug with a hypoglycemic effect and methods for its preparation. To obtain the remedy, a vegetable collection is used containing elecampane crushed rootstalks with roots (lnulae rhizomata (family Asteraceae)), motherwort grass (Leonuri (family Lamiaceae)), lingonberry leaves (Vitis-idaeae (family Ericaceae)) and rosehip fruits (Rosae (family Rosaceae) in a ratio of 11:3:3:3. According to one of the methods, the specified vegetable collection is extracted twice with hot water at a ratio of 1:10 at a temperature of 80°C for 1 hour. Before extraction, the raw materials are soaked in water for 0.5 hours. The combined extracts are maintained at a temperature of 4-8°C for 30 hours and purified by filtration. Another method is that the extraction of plant raw materials is carried out twice with water in an ultrasonic heated bath at a frequency of 40 kHz at a temperature of 80°C for 20 minutes.

EFFECT: obtaining from herbal medicinal raw materials a drug having a pronounced hypoglycemic effect due to the content of up to 20% inulin, 1% arbutin, 1% organic acids and 0.4% rutin and providing an increase in carbohydrate tolerance by 14% under the conditions of a glucose tolerance test.

3 cl, 1 dwg, 2 tbl, 4 ex

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RU 2 773 856 C1

Authors

Dzhavakhyan Marina Arkadevna

Pavets Natalya Romanovna

Paveleva Olesya Konstantinovna

Dul Vyacheslav Nikolaevich

Semkina Olga Aleksandrovna

Lupanova Irina Aloeksandrovna

Trumpe Tatyana Evgenevna

Ferubko Ekaterina Vladimirovna

Martynchik Irina Anatolevna

Mizina Praskovya Georgievna

Sidelnikov Nikolaj Ivanovich

Dates

2022-06-14Published

2021-06-08Filed