FIELD: medicine.
SUBSTANCE: invention relates to the treatment of arthritis or cartilage damage in a human subject. A method for the treatment of arthritis or cartilage damage in a human subject is proposed, providing for the administration to the joint of the human subject of an intra-articular dose, which is about 20-40 mg of polypeptide containing an amino acid sequence SEQ ID NO: 17. A composition for use in the treatment of arthritis in a human subject is also proposed, containing about 20-40 mg of polypeptide containing an amino acid sequence SEQ ID NO: 17, where polypeptide is administered intra-articular.
EFFECT: invention can be used in the regeneration of cartilage, treatment of joint damage, for example joint cartilage damage, or osteoarthritis.
26 cl, 1 dwg, 5 tbl, 1 ex
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