ANTIBODY TO CD40, ITS ANTIGENE-BINDING FRAGMENT AND ITS MEDICAL USE Russian patent published in 2022 - IPC C07K16/28 C12N15/13 A61K39/395 

FIELD: biotechnology.

SUBSTANCE: invention relates to biotechnology and is an antibody to CD40 or its antigene-binding fragment containing a variable region of the light chain of the antibody and a variable region of the heavy chain of the antibody, where the variable region of the light chain of the antibody contains LCDR1, LCDR2 and LCDR3 having certain sequences. The invention also relates to a pharmaceutical composition for the treatment and prevention of a disease or condition mediated by CD40 or CD40L containing the said antibody against CD40 or its antigene-binding fragment and a pharmaceutically acceptable auxiliary substance, diluent or carrier.

EFFECT: invention makes it possible to effectively treat diseases or conditions mediated by CD40 or CD40L.

23 cl, 11 tbl, 11 ex, 4 dwg