FIELD: biotechnology; medicine.
SUBSTANCE: invention relates to the field of biotechnology and medicine, in particular to a monoclonal antibody or its fragment against IL-5; to a pharmaceutical composition for the treatment of a disease associated with human IL-5; to an isolated nucleic acid molecule encoding a monoclonal antibody or its antigen-binding fragment against IL-5; to a recombinant expression vector containing the above-mentioned nucleic acid molecule; to an expressing host cell transformed by the above-mentioned vector; to a method for the production of a monoclonal antibody or its antigen-binding fragment against IL-5; to a method and means for the detection or determination of human IL-5; to a method for the treatment of a disease associated with human IL-5; as well as to the use of the above-mentioned antibody or its antigen-binding fragment, a pharmaceutical composition, an isolated nucleic acid molecule, or a combination thereof in the production of a drug for the prevention or treatment of a disease associated with human IL-5.
EFFECT: obtaining an antibody against IL-5.
20 cl, 5 dwg, 19 tbl, 6 ex
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