FIELD: biochemistry.
SUBSTANCE: invention relates to an antibody or its antigen-binding fragment that specifically binds to human CD3. Also a single chain antibody that specifically binds to human CD3; a bispecific antibody that specifically binds to human CD3; a pharmaceutical composition containing the said antibodies; an isolated nucleic acid molecule encoding the said antibody; a recombinant vector; and a host cell containing the said nucleic acid molecule are disclosed. A method of producing of the said antibody is disclosed.
EFFECT: invention makes it possible to effectively treat diseases associated with CD3.
14 cl, 8 ex, 17 tbl, 11 dwg
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