TRIAZOLE DERIVATIVES WITH MICROBIOCIDAL ACTIVITY Russian patent published in 2022 - IPC C07D417/12 C07D417/14 C07D277/56 A01N43/78 A01P3/00 

FIELD: agriculture.

SUBSTANCE: invention relates to a compound of the formula (I), where R¹ is fluorine; R² is hydrogen; R³ is halogen or C₁-C₄alkyl; R⁴ is hydrogen; R⁵ is C₁-C₆alkyl, C₃-C₆cycloalkyl, C₃-C₆cycloalkylC_1-2alkyl, C₂-C₆alkinyl, phenyl, heterocyclyl or heterocyclylC₁alkyl, where heterocyclyl is a 4- or 6-element nonaromatic monocyclic ring containing 1 oxygen atom, or a 5-9-element nonaromatic annulated or spirocyclic carbobicyclic ring system optionally containing 1 oxygen atom and optionally bound to the rest of a molecule by a methylene (-CH₂-) linker; where any of the specified C₁-C₆alkyl, C₃-C₆cycloalkyl and C₂-C₆alkinyl fragments are optionally substituted with 1-4 groups represented by R⁷, or 1 group represented by R⁸; where any of the specified phenyl or heterocyclyl fragments are optionally substituted with 1 or 2 groups represented by R⁹, or 1 group represented by R¹⁰, or optionally substituted with 1 or 2 groups represented by R⁹ and 1 group represented by R¹⁰; and where the annulated or spirocyclic carbobicyclic ring is optionally substituted with 1 or 2 groups represented by R⁷, or the annulated carbobicyclic ring system is optionally substituted with C₄-C₅cycloalkyl to form a spirocyclic fragment; R⁷ is independently selected from chlorine, bromine, fluorine, cyano, hydroxyl, methyl, trifluoromethyl, methoxy, butoxy, methoxymethyl, cyclopropyl, cyclohexyl, cyclooctyl, cyclopropyl methyl, acetyloxymethyl and ethoxycarbonyl; where cyclopropyl is unsubstituted or substituted with 2 groups of chlorine; R⁸ is phenyl, benzyl or isoxazole, unsubstituted or substituted with 1-3 groups represented by R⁹ or 1 group represented by R¹⁰; R⁹ is independently selected from halogen, cyano, hydroxyl and C₁-C₄alkyl; R¹⁰ is selected from phenyl, benzyl and C₆-C₈cycloalkoxy, each of which is unsubstituted or substituted with 1-3 groups represented by R¹¹; R¹¹ is independently selected from halogen and methyl; X is C-H or N; or its salts. The invention also relates to a fungicidal composition containing the fungicidal effective amount of a compound according to the invention and an agrochemical diluent or carrier. The compound according to the invention is used in a method for control or prevention of an infection of useful plants with phytopathogenic microorganisms.

EFFECT: thiazole derivatives with fungicidal activity.

12 cl, 2 tbl, 2 ex