IMMUNOBIOLOGICAL AGENT AND METHOD FOR ITS USE FOR INDUCTION OF SPECIFIC IMMUNITY AGAINST VIRUSES SARS-COV-2 VARIANT B.1.617.2 (DELTA) AND SARS-COV-2 VARIANT B.1.1.529 (OMICRON) (VARIANTS) Russian patent published in 2022 - IPC C12N7/00 C12N15/861 A61K39/215 

FIELD: biotechnology; immunology; virology.

SUBSTANCE: group of inventions relates to biotechnology, immunology and virology and concerns the prevention of diseases caused by various variants of the SARS-CoV-2 severe acute respiratory syndrome virus. A drug containing at least one expression vector based on the genome of the recombinant human adenovirus strain of the 26th serotype, in which the E1 and E3 regions are deleted, and the ORF6-Ad26 region is replaced by ORF6-Ad5, with a built-in expression cassette SEQ ID NO:1 or SEQ ID NO:2, is proposed. Also described is a remedy containing as an active component at least one expression vector based on the genome of the recombinant strain of human adenovirus of the 5th serotype, in which the E1 and E3 regions are deleted, with an integrated expression cassette SEQ ID NO:1 or SEQ ID NO:3. In addition, a drug is described, which is a mixture of a drug containing as an active component an expression vector based on the genome of the recombinant human adenovirus strain of the 26th serotype, in which the E1 and E3 regions are deleted, and the ORF6-Ad26 region is replaced by ORF6-Ad5, with a built-in expression cassette SEQ ID NO:1 or SEQ ID NO:2 and a remedy containing as an active component an expression vector based on the genome of the recombinant human adenovirus strain of the 26th serotype, in which the E1 and E3 regions are deleted, and the ORF6-Ad26 region is replaced by ORF6-Ad5, with built-in expression cassette SEQ ID NO:1 or SEQ ID NO:2. The technical objective of the claimed group of inventions is to create

EFFECT: group of inventions is aimed at creating remedies for effective induction of an immune response against the SARS-CoV-2 virus variant B.1.617.2 (Delta) and the SARS-CoV-2 virus variant B.1.1.529 (Omicron).

14 cl, 2 dwg, 11 tbl, 18 ex