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2 780 112

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(51)

IPC

A61K31/05(2006-01-01)

A61K31/4164(2006-01-01)

A61P9/10(2006-01-01)

(21) (22)

Application

2022104269, 2022-02-18

(24)

Start date

2022-02-18

(22)

Actual filing date

2022-02-18

(45)

Published

2022-09-19

(72)

Inventor

Stvolinskii Sergei LeibovichFedorova Tatiana NikolaevnaKhutorova Anastasiia ViktorovnaLopachev Aleksandr VasilevichTimoshina Iuliia AlekseevnaKulikova Olga IgorevnaTanashian Marine Movsesovna

(73)

Holder

Federalnoe Gosudarstvennoe Biudzhetnoe Nauchnoe Uchrezhdenie Tsentr Nevrologii»

AGENT WITH NEUROPROTECTIVE ANTI-ISCHEMIC ACTIVITY Russian patent published in 2022 - IPC A61K31/05 A61K31/4164 A61P9/10

Abstract RU 2780112 C1

FIELD: anti-ischemic agents.

SUBSTANCE: invention relates to the use of salicyl-beta-alanyl-L-histidine (salicyl-carnosine) as a neuroprotective anti-ischemic agent in the form of the viability of neurons in a primary culture of rat cerebral cortex cells under conditions of glucose-oxygen deprivation and in a model of NMDA-induced excitotoxicity.

EFFECT: invention provides the ability to use salicyl-beta-alanyl-L-histidine (salicyl-carnosine) as a neuroprotective anti-ischemic agent.

1 cl, 5 dwg, 3 ex

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RU 2 780 112 C1

Authors

Stvolinskii Sergei Leibovich

Fedorova Tatiana Nikolaevna

Khutorova Anastasiia Viktorovna

Lopachev Aleksandr Vasilevich

Timoshina Iuliia Alekseevna

Kulikova Olga Igorevna

Tanashian Marine Movsesovna

Dates

2022-09-19—Published

2022-02-18—Filed