FIELD: biotechnology.
SUBSTANCE: group of inventions is described, including an antibody capable of binding to soluble protein of human extracellular domain CD39 (NTFDase 1) and inhibiting its ATF-phase activity (options), a kit for detection of protein CD39, containing the above-mentioned antibody, and a recombinant host cell producing the above-mentioned antibody. In one of implementations, the antibody contains three sections of HCDR containing amino acid sequences SEQ ID NO: 8-10 and three sections of LCDR containing amino acid sequences SEQ ID NO: 11-13.
EFFECT: invention expands the arsenal of means capable of binding to human CD39 and inhibiting its ATF-phase activity.
33 cl, 13 dwg, 1 tbl, 11 ex
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|---|---|---|---|
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|
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|
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| IMMUNOCYTOKINES AND THEIR USE | 2021 |
|
RU2818371C1 |
