FIELD: biotechnology.
SUBSTANCE: invention relates to the field of biotechnology, in particular to new antibodies, and can be applied in medicine. The invention discloses a bispecific antibody in which Fab fragments bind to NKG2D and 5T4 receptors and Fc fragment binds to CD16.
EFFECT: invention can be used to stimulate a specific immune response in the treatment of malignant neoplasms that overexpress human trophoblastic glycoprotein (5T4).
25 cl, 10 ex, 12 tbl, 46 dwg
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Authors
Dates
2023-01-23—Published
2018-05-23—Filed