FIELD: biochemistry.
SUBSTANCE: invention relates to a bispecific binding molecule which specifically binds to human ROR1 and human CD3, as well as to an immunoconjugate, a pharmaceutical composition, a kit and a bottle containing it. Also disclosed is an isolated nucleic acid molecule coding said antibody, as well as a vector and a cell containing same. Invention also relates to a method of producing a bispecific binding molecule involving the use of said cells.
EFFECT: invention is effective for treating ROR1-positive cancer in a patient.
50 cl, 29 dwg, 6 tbl, 5 ex
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