POLYMORPHOUS FORMS OF SODIUM BENZOATE AND THEIR USE Russian patent published in 2022 - IPC C07C63/08 A61K31/192 C07C51/43 A61P25/18 A61P25/28 

Abstract RU 2782627 C2

FIELD: medicine.

SUBSTANCE: invention relates to a method for the production of a polymorphous form of sodium benzoate, which has a diffraction radiograph containing characteristic peaks at a reflection angle 2θ of 4.3, 5.9, 7.1, 8.6, 10.1, 10.7, 12.9, 13.8, 14.4, 17.2, 17.7, 18.5, 21.5, 22.0, 22.6, 23.7, 25.1, 25.9, 26.2, 26.9, 27.9, 28.2, 28.8, 29.1, 29.7, 30.2, 31.2, 33.2, 34.9, 35.8, 36.1, and 39.3.

EFFECT: method is developed for the production of a new polymorphous form of sodium benzoate, which can be used in the treatment and/or reduction in the risk of a neuropsychiatric disorder, for example, schizophrenia, psychotic disorders, depressive disorders, or Alzheimer’s disease.

5 cl, 24 dwg, 5 tbl, 14 ex

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RU 2 782 627 C2

Authors

Tsai, Guochuan Emil

Wang, Ching-Cheng

Hsieh, Tien-Lan

Dates

2022-10-31Published

2017-10-24Filed