FIELD: medicine, pharmaceutics.
SUBSTANCE: invention relates to polymorphic forms of (2S)-(4E)-N-methyl-5-[3-(5-isopropoxypyridin)yl]-4-penten-2- amine of "п"-hydroxybenzoate, to pharmaceutic composition, containing said polymorph(s), as well as to their application for treatment of CNS disorders.
EFFECT: obtained and described are novel polymorphic forms of (2S)-(4E)-N-methyl-5-[3-(5-isopropoxypyridin)yl]-4-penten-2-amine of "п"-hydroxybenzoate, which can be applied to patients, subjected or possessing diseases and disorders, such as central nervous system diseases, for treatment and/or prevention such disorders
13 cl, 4 ex, 2 tbl
Title |
Year |
Author |
Number |
HYDROXYBENZOATE SALTS OF METANICOTINIC COMPOUNDS |
2005 |
- Mun'Os Khulio A.
- Dzhenus Dzhon
- Mur Dzhejms R.
|
RU2409566C2 |
NONHYGROSCOPIC CRYSTALLINE 5-[(Z)-(5-FLUORO-2-OXO-1,2-DIHYDRO-3H-INDOL-3-YLIDENE)METHYL]-N-[(2S)-2-HYDROXY-3-MORPHOLIN-4-YLPROPYL]-2,4-DIMETHYL-1H-PYRROL-3-CARBOXAMIDE MALEATE SALT, PHARMACEUTICAL COMPOSITION AND METHOD FOR CANCER TREATMENT |
2004 |
- Blasko Andrej
- Tszin' Tsinvu
- Lu Tsjun'
- Morejdzhis Majkl Ehntoni
- Song Dong
- Vondervell Brenda S'Ju
|
RU2319702C2 |
SYNTHESIS AND NEW SALINE FORMS OF (R)-5-((E)-2-(PYRROLIDIN-3-YLVINYL)PYRIMIDINE |
2009 |
- Akireddi Srinivisa Rao
- Bkhatti Balvinder Singkh
- Katbertson Timoti Dzh.
- Dall Gari Moris
- Miller Krehjg Kharrison
- Mitchener Ml., Dzhozef Pajk
- Mun'Os Khulio A.
- Otten Piter Al'Bert
|
RU2533819C2 |
SOLID FORMS OF (1,1-DIOXO-4-THIOMORPHOLINYL) - [6 - [[3- (4-FLUOROPHENYL) -5-METHYL-4-ISOXAZOLYL] METHOXY] -3-PYRIDINYL] METHANONE |
2012 |
- Dott Paskal
- Grassmann Olaf
- Kammerer Mikhel
- Manns Ioakhim
- Shvitter Urs
- Tomas Endryu
- Vittenbakh Nikol
|
RU2618524C2 |
SYNTHESIS AND NOVEL SALT FORMS OF (R)-5-((E)-2-PYRROLIDIN-3-YLVINYL)PYRIMIDINE |
2014 |
- Akireddi Srinivasa Rao
- Bkhatti Balvinder Singkh
- Katbertson Timoti Dzh.
- Dall Gari Moris
- Miller Krejg Kharrison
- Mitchener Ml. Dzhozef Pajk
- Munos Khulio A.
- Otten Piter Albert
|
RU2700796C2 |
(3-ARYLSULPHONYL QUINOLIN-8-YL-DIALKYL-AMINES - SELECTIVE SEROTONIN 5-HT RECEPTOR ANTAGONISTS, METHODS FOR PRODUCTION AND USE THEREOF |
2012 |
- Ivashchenko Andrej Aleksandrovich
- Savchuk Nikolaj Filippovich
- Ivashchenko Aleksandr Vasil'Evich
|
RU2500672C1 |
POSITIVE ALLOSTERIC MODULATORS OF NICOTINIC ACETYLCHOLINE RECEPTOR |
2012 |
- Eskildsen Jergen
- Sams Anette Graven
- Pjushl Ask
|
RU2604737C2 |
2-ALKYLAMINO-3-ARYLSULPHONYLCYCLOALKANO [e OR d]PYRAZOLO[1,5-a] PYRIMIDINES SEROTONIN 5-HT RECEPTOR ANTAGONISTS, METHODS FOR MAKING AND APPLYING THEREOF |
2008 |
- Ivashchenko Aleksandr Vasil'Evich
- Savchuk Nikolaj Filippovich
- Ivashchenko Andrej Aleksandrovich
|
RU2377244C1 |
CRYSTALLINE SOLID FORM OF (2S,5Z)-2-AMINO-7-(ETHANEIMIDOYLAMINO)-2-METHYLHEPT-5-ENOIC ACID 1.5 HYDROCHLORIDE, METHOD FOR ITS PREPARING, PHARMACEUTICAL COMPOSITION BASED ON THEREOF |
2003 |
|
RU2314290C2 |
(2S,3R-)-N-(2-((3-PYRIDINYL)METHYL)-1-AZABICYCLO[2,2,2]OCT-3-YL)BENZOFURANE-2-CARBOXAMIDE, NEW SALT FORMS AND METHODS FOR PREPARING THEM |
2008 |
- Bensherif Meruan
- Benson Lajza
- Dall Gari Moris
- Fedorov Nikolaj
- Gatto Gregori Dzh.
- Dzhenus Dzhon
- Dzhordan Kristen G.
- Meht'Ju Dzhejkob
- Mazurov Anatolij A.
- Mjao Lan'
- Mun'Os Khulio A.
- Pfajffer Inigo
- Pfajffer Sondra
- Fillips Tereza I.
|
RU2476220C2 |