SUBSTITUTED HYDRAZIDES OF 2-DIARYLMETHYLENE HYDRAZONE-5,5-DIMETHYL-4-OXOHEXANOIC ACIDS EXHIBITING ANTI-INFLAMMATORY ACTIVITY Russian patent published in 2022 - IPC C07C251/84 C07C251/86 C07C251/88 C07C249/16 A61K31/16 A61P29/00 

Abstract RU 2783158 C2

FIELD: chemistry.

SUBSTANCE: invention relates to the field of organic chemistry, to new biologically active substances of the class of derivatives of 2,4-dioxohexanoic acids. Proposed are substituted hydrazides of 2-diarylmethylene hydrazone-5,5-dimethyl-4-oxohexanoic acids (1 to 5), wherein R, R1, R2 are defined in the claim, exhibiting pronounced anti-inflammatory activity with low toxicity.

EFFECT: creation of new biologically active substances with pronounced anti-inflammatory activity.

1 cl, 1 tbl, 6 ex

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RU 2 783 158 C2

Authors

Siutkina Alena Ivanovna

Igidov Nazim Musabekovich

Chashchina Svetlana Viktorovna

Sharaveva Iuliia Olegovna

Shipilovskikh Sergei Aleksandrovich

Dates

2022-11-09Published

2021-04-05Filed