FIELD: chemistry.
SUBSTANCE: invention relates to a method for producing 3-azolylpropanols used as initial compounds for producing biologically active substances for medical and agricultural purposes. Method for producing 3-azolylpropanols by the general formula I
wherein Z and Y each independently means CH or N, or Z and Y together mean an atom chain C-CH=CH-CH=CH-C forming a nucleus annelated with the azole ring, consisting in alkylating the corresponding azoles with trimethylene carbonate in the presence of bases of alkali metal azolates or tertiary amines as catalysts in an amount from 0.01 to 0.05% mol. in an aprotic weakly polar solvent while heating at a temperature of 110 to 155 °C.
EFFECT: ensured production of 3-azolylpropanols.
1 cl, 7 ex
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Authors
Dates
2022-12-23—Published
2022-04-11—Filed