CANCER Russian patent published in 2022 - IPC C12Q1/68 

FIELD: biotechnology; medicine.

SUBSTANCE: present invention relates to cancer and, in particular, to diagnostic and prognostic methods in cancer and metastasis, and biomarkers of these conditions. A method for diagnostics of a subject suffering from cancer or metastasis, or having predisposition to them, or provision of a prediction of a subject’s condition is proposed. The method includes detection of a concentration of peptide SEQ ID No: 3 in a sample obtained from the subject, and comparison of this concentration with a reference concentration of peptide SEQ ID No: 3 in a subject not suffering from cancer or metastasis. Increase in the concentration of peptide SEQ ID No: 3 compared to the reference concentration means that the subject suffers from cancer or metastasis, or has predisposition to them, or the subject’s condition has a negative prediction. A kit for diagnostics of a subject suffering from cancer or metastasis, or having predisposition to them, or for provision of a prediction of a subject’s condition, and the use of peptide SEQ ID No: 3 as a diagnostic or prognostic biomarker of cancer or metastasis are proposed.

EFFECT: invention provides for the use of peptide “T14” (SEQ ID No: 3) for the diagnostics of cancer.

7 cl, 62 dwg, 10 ex