METHOD FOR TREATING PERIODONTITIS USING MULTIPOTENT MESENCHYMAL STEM CELLS OF HUMAN TOOTH PULP AND AN OSTEOGENESIS STIMULATOR AGENT Russian patent published in 2022 - IPC A61K35/28 A61P1/02 

Abstract RU 2785009 C1

FIELD: dentistry.

SUBSTANCE: invention relates to the field of medicine, in particular, to dentistry, and can be used for treating periodontitis in an experiment. Method includes the stage of extracting multipotent mesenchymal stem cells (MMSCs) from the pulp of a removed impacted human tooth. Powdered alloplant osteogenesis stimulator in an amount of 0.1 g is pre-soaked in a 0.9% sodium chloride solution and then mixed with 150 thousand MMSCs. The resulting mixture is introduced into the bone (periodontal) pockets of rats in the area of the second maxillary molar using a carver and fixed with a Septopack protective bandage; the treatment consists of 3 procedures at an interval of 5 days.

EFFECT: possibility of increasing the therapeutic effect by enhancing the bone tissue regeneration and preventing complications.

1 cl, 1 ex

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RU 2 785 009 C1

Authors

Khajbullina Rasima Rashitovna

Danilko Kseniya Vladimirovna

Shangina Olga Ratmirovna

Valeeva Gulnara Akhmetovna

Lopatina Natalya Viktorovna

Gerasimova Larisa Pavlovna

Dates

2022-12-01Published

2022-02-01Filed