BIOLOGICALLY ACTIVE QUADROCOMPLEX FOR REGULATION OF SKIN MICROBIOTA BIODIVERSITY Russian patent published in 2023 - IPC A61K8/18 A61K8/9789 A61K33/28 A61K36/61 A61Q17/00 A61Q19/10 

FIELD: perfumery and cosmetic industry.

SUBSTANCE: inventions group relates to perfumery and cosmetic industry for hand and/or body skin care. Biological complex active against bacteria selected from Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Bacillus cereus, Candida albicans, Staphylococcus epidermidis and Micrococcus luteus, and intended for use in liquid soap, consisting of: a) essential oil of tea tree (Melaleuca alternifolid), b) alpha-bisabolol, c) 1,8-cineole obtained from eucalyptus leaves (Eucalyptus spp.), d) an aqueous solution of citric acid and silver citrate, where the specified aqueous solution contains 19-23% of the mass. citric acid and 2280-2640 ppm silver citrate and where the mass ratio of components a:b:c:g is (0.1-0.5):(0.05-0.3):(0.05-0 .35):(0.01-0.2) respectively. Liquid soap containing 0.3-0.7% of the mass. the biological complex described above.

EFFECT: above biological complex is used to regulate the skin microbiota, which synergistically inhibits the growth of the population of opportunistic microorganisms selected from Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Bacillus cereus, Candida albicans, while maintaining the representatives of the normal microflora of Staphylococcus epidermidis and Micrococcus luteus.

4 cl, 6 tbl, 5 ex