PREFERENTIAL PAIRING OF ANTIBODY DOMAIN Russian patent published in 2023 - IPC C07K16/28 C07K16/46 

Abstract RU 2792440 C2

FIELD: biochemistry.

SUBSTANCE: invention relates to a method for producing an antigen-binding molecule (ABM), which is a heterodimeric IgG antibody.

EFFECT: invention provides improved pairing of heavy and light chains of an antibody that maintains the correct pairing of HC and LC in an IgG bispecific antibody.

9 cl, 5 dwg, 3 tbl, 3 ex

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RU 2 792 440 C2

Authors

Ryuker, Florian

Benish, Maksimilian

Dates

2023-03-22Published

2018-02-02Filed