FIELD: biotechnology.
SUBSTANCE: proposed is a pharmaceutical composition for treating diseases, containing an effective amount of a multispecific antibody from the subclass of human IgG1, and a pharmaceutically acceptable carrier is presented, wherein said antibody includes: a first light chain, a first heavy chain containing a first heteromonomeric Fc-region polypeptide, a second light chain and a second heavy chain containing a second heteromonomeric Fc-region polypeptide; and is produced as a result of cultivation of a mammalian cell in a culture medium.
EFFECT: possibility of producing a pharmaceutical composition with an active product and a low content of impurities intended for treating diseases.
9 cl, 6 dwg, 11 tbl, 7 ex
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