CHEMICAL COMPOUNDS Russian patent published in 2023 - IPC C07D471/14 A61K31/4375 A61P31/20 

FIELD: pharmaceuticals.

SUBSTANCE: invention relates to a compound of Formula I or a pharmaceutically acceptable salt thereof, wherein W is N; Y is C; R¹ is absent; R² is either halogen, hydroxy or cycloalkyl; R³ is -OR¹²; R⁴ is H; R⁵ is H; R⁶ and R⁷ together form a 3- to 8-membered cycloalkyl ring, optionally substituted with R¹⁵, R^15', R¹⁶ and/or R^16'; R⁸ is H; R⁹ is H; R¹⁰ is -COOH; R¹¹ is H; R¹² is C_1-6 alkyl substituted with methoxy or cyclopropyl; and R¹⁵, R¹⁵, R¹⁶ and/or R¹⁶' are independently C_1-6 alkyl. The invention also relates to a pharmaceutical composition containing a therapeutically effective amount of a compound of Formula I.

EFFECT: obtaining new compounds and a pharmaceutical composition based on them which can be used in medicine as effective agents for the treatment of hepatitis B.

8 cl, 3 tbl, 36 ex