COMPOUND BASED ON DIHYDRONAPTHYRIDINONE, METHOD OF ITS OBTAINING, AND ITS USE IN MEDICINE Russian patent published in 2023 - IPC C07D471/04 C07D401/14 A61K31/4375 A61K31/4353 A61P31/00 A61P35/00

Abstract RU 2809869 C1

FIELD: pharmaceuticals.

SUBSTANCE: invention relates to a compound based on dihydronaphthyridinone of formula (I), where A, B, R₁-R₆ are defined in the claims, and also relates to its pharmaceutically acceptable salt and stereoisomers. The compound has a selective inhibitory effect on RIPK1.

(I)

EFFECT: pharmaceutical composition containing a compound of formula (I) and its use in the preparation of a medicament for the treatment of diseases or conditions associated with RIPK1 are also provided.

16 cl, 3 tbl, 90 ex

Similar patents RU2809869C1

Title	Year	Author	Number
SUBSTITUTED HETEROCYCLIC FUSED CYCLIC COMPOUND, METHOD FOR PRODUCTION THEREOF AND PHARMACEUTICAL USE THEREOF	2020	Zhou, Fusheng Jiang, Tao Lin, Chonglan Cai, Lijian He, Wan Lan, Jiong	RU2815814C1
NITROIMIDAZOLE DERIVATIVE AGAINST PULMONARY TUBERCULOSIS	2016	Luo, Wei Ding, Charles Z. Huang, Zhigang Chen, Shuhui	RU2675622C1
1,2,4-TRIAZINE-3-AMINE DERIVATIVES	2011	Kongriv Majlz Styuart Endryus Stiven Filipp Mejson Dzhonatan Stiven Richardson Kristin Meri Braun Zhajls Albert	RU2771819C2
FGFR INHIBITOR, METHOD FOR PRODUCTION AND APPLICATION THEREOF	2019	Deng, Haibing Yu, Hongping Chen, Zhui Xu, Yaochang	RU2771526C1
HETEROBICYCLO-SUBSTITUTED-[1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINE COMPOUNDS WITH A2A ANTAGONIST PROPERTIES	2013	Ali Amdzhad Lo Majkl Man-Chu Lim Jeon-Khee Stemford Endryu Kuan Zhuntsze Tempest Pol Yuj Yunun Khuan Syankhaj Khenderson Timoti Dzh. Kim Dzae-Khun Bojs Kristofer Ting Polin Chzhen Tszyunin Mettsger Edvard Tsorn Nikolas Syao Dun Gallo Dzhokonda V. Von Uolter U Khepin Den Tsyaolin	RU2671628C2
BICYCLIC DERIVATIVES	2019	Dyukre, Per Potra, Fransua Razho, Deniz Takhtaui, Shuaib	RU2794894C2
TLR7 AGONISTS	2019	Webber, Stephen, E. Appleman, James, Richard	RU2817014C2
1,2,4-TRIAZOLONE DERIVATIVE	2011	Kuvada Takesi Josinaga Mitsukane Isizaka Tomoko Vakasugi Dajsuke Sirokava Sin-Iti Khattori Nobutaka Simazaki Euiti Mijakosi Naoki	RU2566754C2
AZALACTAM COMPOUNDS AS HPK1 INHIBITORS	2019	Gallego, Rebekka Enn Nair, Sadzhiv Krishnan Kania, Robert Stiven Akhmad, Omar Kkhaled Dzhonson, Ted Uillyam Tattl, Dzhejmison Brajs Dzhalej, Mekhran Maktig, Mishel Enn Chzhou, Dakhuej Del Bel, Mettyu L. Chzhou, Ru Khe, Mining Shmitt, Anne-Mari Dechert	RU2801140C2
6-5 CONDENSED RINGS AS C5a INHIBITORS	2018	Fan, Pingchen Lange, Christopher W. Lui, Rebecca M. Malathong, Viengkham Mali, Venkat Reddy Punna, Sreenivas Singh, Rajinder Tanaka, Hiroko Zeng, Yibin Zhang, Penglie	RU2780338C2

RU 2 809 869 C1

Authors

Zhou, Fusheng

Xu, Xiaoming

Zhang, Leitao

Li, Xin

Tang, Lili

Lan, Jiong

Dates

2023-12-19—Published

2021-02-09—Filed