FIELD: medicine; gynecology.
SUBSTANCE: use of 11-(4-tert-butylbenzyl)-2,4,5,11-tetrahydro-3H-[1,3]diazepino[1,2-a]benzimidazole hydrobromide of formula 1 as a blocker of ionotropic glutamate receptors and for instance for the treatment of diseases of the nervous system associated with the imbalance of the glutamatergic system.
EFFECT: antagonistic activity against all three main subtypes of ionotropic glutamate receptors with IC50 to 20 μM.
1 cl, 1 dwg, 3 tbl
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