FIELD: medicine.
SUBSTANCE: group of inventions relates to the methods for treating cancer with an activating alteration rearranged during transfection (RET-altered cancer). Variants of a method of treating cancer having an activating transfection-rearranged alteration (RET-altered cancer) in a subject in need thereof are provided, comprising administering to the subject a therapeutically effective amount, 300 mg or 400 mg, of compound 1 or a pharmaceutically acceptable salt thereof once a day.
EFFECT: achievement of the maximum therapeutic effect while maintaining the safety of the medicinal product.
37 cl, 13 dwg, 2 tbl, 3 ex
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Authors
Dates
2023-08-01—Published
2019-04-03—Filed