METHOD OF MODELING COMBINED PATHOLOGY OF LUNG CARCINOMA AND TUBERCULOSIS Russian patent published in 2023 - IPC G09B23/28 

FIELD: medicine, experimental oncology and phthisiology.

SUBSTANCE: invention can be used for modeling combined pathology of lung carcinoma and tuberculosis. C57BL/6 mice are simultaneously inoculated into the lateral vein of the tail with a suspension of Mycobacterium tuberculosis strain at a dose of 10⁶ microbial cells in 0.2 ml of saline and transplanted into the muscle of the right thigh of the animal with a 10% suspension in saline of Lewis epidermoid carcinoma of the lung in a volume of 0.2 ml. Then the development of pathology is controlled on the 14th and 21st day.

EFFECT: invention provides for the creation of an experimental highly reproducible model of the combined pathology of cancer and tuberculosis, which most accurately reflects the clinical course of each of the diseases.

3 cl, 14 dwg, 6 tbl, 2 ex