FIELD: medicine, pharmaceutics.
SUBSTANCE: present invention refers to using an immunotherapeutic agent containing cell wall fragments of the virulent strain Mycobacterium tuberculosis for preparing a therapeutic agent used for the primary prevention of tuberculosis in individuals suffered the exposure of an infectious agent with a negative tuberculin skin test (TSK) response detected.
EFFECT: immunotherapeutic agent is able to stimulate the protective response, which is more effective than that elicited by common BCG vaccine, and reduces viable bacteria count in lungs and spleen of the individuals recently infected M tuberculosis.
14 cl, 2 tbl, 1 ex
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Authors
Dates
2015-03-10—Published
2009-09-03—Filed