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2 801 630

(13)

(51)

IPC

A61K47/68(2017-01-01)

C07K16/28(2006-01-01)

A61P35/00(2006-01-01)

(21) (22)

Application

2021128538, 2020-03-05

(24)

Start date

2020-03-05

(22)

Actual filing date

2020-03-05

(45)

Published

2023-08-11

(72)

Inventor

Park, Chang SikChoi, Min JiJang, Tae IkPark, Yun-HeeSong, Ho YoungBaek, JuyuelKim, Sung MinLee, Hyeun JoungLee, Ju YoungKim, Hyoung RaeLee, Kun JungKim, Yong ZuLee, Chang SunChae, JeiwookLee, Sang PilShin, Ji-YoungYoon, SunhaChoi, YunseonPark, Jae EunLee, JisuPark, Bum-ChanPark, Young Woo

(73)

Holder

Legochem Biosciences, Inc.Y-Biologics Inc.

ANTIBODY-DRUG CONJUGATES INCLUDING ANTIBODY AGAINST HUMAN DLK1 AND THEIR USE Russian patent published in 2023 - IPC A61K47/68 C07K16/28 A61P35/00

Abstract RU 2801630 C2

FIELD: pharmaceuticals.

SUBSTANCE: invention relates to novel antibody-drug conjugates (ADCs) containing an antibody that binds to DLK1, or an antigen-binding fragment thereof, and a pharmaceutical composition containing the said conjugates for the prevention or treatment of cancer associated with DLK1 expression.

EFFECT: obtaining antibody-drug conjugates including antibody against human DLK1.

59 cl, 1 dwg, 3 tbl, 3 ex

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RU 2 801 630 C2

Authors

Park, Chang Sik

Choi, Min Ji

Jang, Tae Ik

Park, Yun-Hee

Song, Ho Young

Baek, Juyuel

Kim, Sung Min

Lee, Hyeun Joung

Lee, Ju Young

Kim, Hyoung Rae

Lee, Kun Jung

Kim, Yong Zu

Lee, Chang Sun

Chae, Jeiwook

Lee, Sang Pil

Shin, Ji-Young

Yoon, Sunha

Choi, Yunseon

Park, Jae Eun

Lee, Jisu

Park, Bum-Chan

Park, Young Woo

Dates

2023-08-11—Published

2020-03-05—Filed