METHOD OF DETERMINING THE ACTIVITY OF BOTULINUM TOXIN USING CELLS Russian patent published in 2023 - IPC C07K16/12 G01N33/50 G01N33/53 G01N33/68 C12N5/793 

Abstract RU 2803123 C2

FIELD: biotechnology.

SUBSTANCE: following is presented: antibodies that specifically bind to SNAP25FL, an antibody composition and a kit for determining the activity of botulinum toxin, as well as a hybridoma cell for the production of an antibody according to any of paragraphs 1-3, which is a hybrid of a spleen cell and a mouse myeloma cell. Besides, a method of determining the activity of botulinum toxin and a method of detecting botulinum toxin are presented. The invention provides a new antibody having a significantly higher binding affinity and specificity for SNAP25FL.

EFFECT: it is expected that the specified antibody will be actively used in the pharmaceutical and cosmetic fields.

8 cl, 31 dwg, 19 tbl, 18 ex

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RU 2 803 123 C2

Authors

Lee Chee Gun

Oum, Ji Hyun

Ajay, Vijayakumar

Gui Xiangai

Dates

2023-09-06Published

2019-08-19Filed