FIELD: medicine.
SUBSTANCE: present invention relates to a compound of the formula
,
where R1 is H; R2 and R3 are OH; R4 is O-C1-6alkyl; R5 is NH, and R6 is 2-pyrrolino-daunozamine or 2-pyrrolino-epidaunozamine, which is used for suppression of fibrosarcoma cell growth. The invention also relates to a pharmaceutical composition and to a synergetic combined preparation containing this compound, as well as to a method for suppression of fibrosarcoma cell growth.
EFFECT: provision of an anthracycline compound containing 2-pyrrolino-group, which increases anticancer activity, while saving a good safety profile.
20 cl, 4 tbl, 4 ex
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