USE OF PHOSPHOLIPID EMULSION COMPRISING DIHYDROQUERCETIN TO PROTECT DONOR ORGAN TISSUE AND PREVENT ITS REJECTION IN TRANSPLANTOLOGY Russian patent published in 2023 - IPC A61K9/107 A61K31/353 A61K47/18 A61K47/24 A61P37/06 

Abstract RU 2804132 C1

FIELD: transplantation.

SUBSTANCE: present invention relates to the use of a phospholipid emulsion comprising an effective amount of dihydroquercetin (DHA) for the protection of donor organ tissue during transplantation, which uses a phospholipid emulsion comprising the following components in g per 100 ml: glycine 3.5± 0.5; egg lecithin 3.5± 0.8; dihydroquercetin 0.35± 0.1; water is the rest.

EFFECT: increase in the time of rejection of transplanted tissue, which is expressed in a decrease in the rate of graft resorption, a decrease in the level of oxidative stress, and prevention of inflammatory reactions of phagocytes.

4 cl, 9 tbl, 2 dwg

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RU 2 804 132 C1

Authors

Tsvetkov Maksim Viacheslavovich

Evteev Anton Vladimirovich

Matveev Dmitrii Valentinovich

Dates

2023-09-26Published

2023-03-09Filed