METHOD AND TRANSPLANT FOR TREATMENT OF LIVER FAILURE Russian patent published in 2011 - IPC A61B17/00 A61K35/28 A61K35/407 A61P1/16 

FIELD: medicine.

SUBSTANCE: group of inventions relates to medicine and can be applied for treatment of liver failure. Transplant includes three-dimensional biocompatible biodegradable porous matrix, which has total volume not less than 0.05 cm³ and the smallest linear size not less than 0.2 mm, pore size 2-500 mcm, total porosity 50-97%, and implanted on it allogenic progenitor cells of bone marrow and allogenic liver cells, concentration of liver and bone marrow cells being 2×10⁶-15×10⁶ cells per 1 cm³ of matrix and ratio of bone marrow cells to liver cells being from 1:1 to 1:4. In realisation of method of treating liver failure transplant is placed into mesentery of small intestine.

EFFECT: group of inventions makes it possible to increase term of cell survival, activate their proliferation.

6 cl, 7 dwg