METHOD AND TRANSPLANT FOR TREATMENT OF LIVER FAILURE Russian patent published in 2011 - IPC A61B17/00 A61K35/28 A61K35/407 A61P1/16 

FIELD: medicine.

SUBSTANCE: group of inventions relates to medicine and can be applied for treatment of liver failure. Transplant includes heterogenic biocompatible biodegradable gel, which has total volume not less than 0.1 ml and the smallest linear size not less than 0.2 mm, pore size 30-500 mcm, total porosity 50-98%, implanted on it autologous progenitor cells of bone marrow after their cultivation in vitro and cultivated autologous liver cells, concentration of liver and bone marrow cells being 2×10⁶-15×10⁶ cells per of 1 cm³ of heterogeneous gel and ratio of bone marrow cells to liver cells being from 1:1 to 1:4. In method of treating liver failure transplant is placed into parenchyma of liver and/or mesentery of small intestine.

EFFECT: group of inventions makes it possible to increase term of cell survival, activate their proliferation.

4 cl, 6 dwg