FIELD: organic chemistry.
SUBSTANCE: invention relates to a method of producing methyl 1-{[2-(2-chlorobenzoyl)hydrazinylidene](2-chlorophenyl)methyl}cycloalkane-1-carboxylates of formula 1a, b with antioxidant activity, which can be used as medicinal products in pharmacology. The method involves the interaction of 2,5-di(2-chlorophenyl)-1,3,4-oxadiazole 2 with methyl esters of 1-bromocycloalkanecarboxylic acids 3a, b and zinc in toluene, followed by treatment of the reaction mass and isolation of the target products, according to the following scheme:
EFFECT: provision of a simple method of the synthesis of methyl 1-{[2-(2-chlorobenzoyl)hydrazinylidene](2-chlorophenyl)methyl}cycloalkane-1-carboxylates 1a, b.
1 cl, 1 tbl, 3 ex
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