FIELD: organic chemistry.
SUBSTANCE: invention relates to the new use of 1'-aryldispiro[cycloalkane-1,3'-azetidine-2',3''-indoline]-2'',4'-diones, expressed by formulas 1a-c as analgesics.
EFFECT: suppression of pain sensitivity provided by compounds of the specified structure 1a-c, which have pronounced analgesic activity.
1 cl, 1 tbl, 4 ex
Title | Year | Author | Number |
---|---|---|---|
USE OF N-[1-ARYL-3-OXO-2-AZASPIRO[3.5]NONAN-2-YL]BENZAMIDES AS ANALGESIC MEDICINAL PRODUCTS | 2023 |
|
RU2810704C1 |
USE OF 3,3'-(1,4-PHENYLENE)BIS[2-ARYL-2-AZASPIRO[3.5]NONAN-1-ONES] AS AGENTS WITH ANALGESIC ACTIVITY | 2023 |
|
RU2808986C1 |
USE OF 1-[(Z)-3-((E)-3-ARYL-1-HYDROXYALLYLIDENE)-2-OXOCHROMAN-4-YL]CYCLOHEXANE CARBOXYLATES AS AGENTS HAVING ANALGESIC ACTIVITY | 2024 |
|
RU2827552C1 |
USE OF N-[2-(1-OXO-3,5-DIPHENYL-2-AZASPIRO[5.5]UNDEC-3-EN-2 IL)PHENYL]-3-BROMOBENZAMIDE AS ANALGESIC | 2023 |
|
RU2808999C1 |
USE OF 1'-(1-METHOXYPHENYL)DISPIRO[CYCLOHEXANE-1,3'-AZETIDINE-2',3''-INDOLINE]-2'',4'-DIONE AS CYTOTOXIC DRUG | 2024 |
|
RU2831249C1 |
USE OF 2-(4-BROMOPHENYL)-3-(2-PHENYLETHENYL)-2-AZASPIRO[3.5]NONAN-1-ONE AS AN AGENT WITH ANALGESIC ACTIVITY | 2023 |
|
RU2808988C1 |
USE OF 1-((2-BENZOYLHYDRAZINYL)(4-METHYLPHENYL)METHYL)CYCLOHEXANE-1-CARBOXYLATE AS AGENT HAVING ANALGESIC ACTIVITY | 2024 |
|
RU2831362C1 |
METHOD OF PRODUCING METHYL 1-{[2-(2-CHLOROBENZOYL)HYDRAZINYLIDENE](2-CHLOROPHENYL)METHYL}CYCLOALKANE-1-CARBOXYLATE | 2023 |
|
RU2809000C1 |
METHOD FOR OBTAINING DISPYROINDOLINONES BASED ON 5-INDOLIDENE-2-THIOHIDANTOINES | 2020 |
|
RU2756463C1 |
METHOD OF PRODUCING 5-ARYL-2-METHYL-1,3-DIOXO-2-AZASPIRO[5,5] UNDECANE-4-CARBONITRILES AND AGENT EXHIBITING ANALGESIC ACTIVITY | 2011 |
|
RU2455284C1 |
Authors
Dates
2023-12-05—Published
2023-05-03—Filed