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(19)

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2 809 257

(13)

(51)

IPC

C07D498/04(2006-01-01)

C07D519/00(2006-01-01)

A61K31/5365(2006-01-01)

A61P25/28(2006-01-01)

A61P35/00(2006-01-01)

(21) (22)

Application

2021117840, 2019-11-20

(24)

Start date

2019-11-20

(22)

Actual filing date

2019-11-20

(45)

Published

2023-12-08

(72)

Inventor

Kun, BerndGreter, UveKhornsperger, BenuaRikhter, KhansKroll, KarstenGrebke Tsbinden, KatrinO'Khara, FionnRombakh, DideLuts, Marius Daniel Rinaldo

(73)

Holder

F. Hoffmann-La Roche Ag

HETEROCYCLIC COMPOUNDS Russian patent published in 2023 - IPC C07D498/04 C07D519/00 A61K31/5365 A61P25/28 A61P35/00

Abstract RU 2809257 C2

FIELD: pharmaceuticals.

SUBSTANCE: invention relates to new heterocyclic compounds of general formula (I), where A, B, L, X, R¹, R², R³ and R⁴ are as indicated in the claims, as well as to a method for their preparation and pharmaceutical composition containing the indicated compounds.

EFFECT: compounds have inhibitory activity against monoacylglycerol lipase (MAGL).

34 cl, 2 tbl, 74 ex

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RU 2 809 257 C2

Authors

Kun, Bernd

Greter, Uve

Khornsperger, Benua

Rikhter, Khans

Kroll, Karsten

Grebke Tsbinden, Katrin

O'Khara, Fionn

Rombakh, Dide

Luts, Marius Daniel Rinaldo

Dates

2023-12-08—Published

2019-11-20—Filed