NEW CRYSTAL FORM OF 1-[2-(1-METHYLIMIDAZOL-4-YL)ETHYL]PERHYDROAZINE-2,6-DIONE AND ITS PHARMACEUTICAL USE Russian patent published in 2023 - IPC C07D401/06 A61K31/454 A61P31/12 

Abstract RU 2809992 C1

FIELD: pharmaceuticals.

SUBSTANCE: invention relates to the crystalline form of 1-[2-(1-methylimidazol-4-yl)ethyl]perhydroazine-2,6-dione, characterized by the positions of the peaks in the powder X-ray diffraction pattern 2θ, deg.: 16.4±0.2 and 23.8± 0.2, as well as the method of its preparation, pharmaceutical composition and medicinal product based on it.

EFFECT: obtaining a new crystalline form of the compound which is stable, highly soluble, slightly hygroscopic, reduces the production of inflammatory cytokines and chemokines in a patient with acute respiratory viral infection and can be used in medicine for the treatment and/or prevention of viral diseases of the respiratory tract.

26 cl, 10 dwg, 4 tbl, 10 ex

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RU 2 809 992 C1

Authors

Nebolsin Vladimir Evgenevich

Dates

2023-12-20Published

2022-06-24Filed