METHOD OF PREDICTING RISK OF ADAPTATION FAILURE IN PEOPLE WORKING IN UNFAVORABLE CLIMATIC CONDITIONS OF ARCTIC Russian patent published in 2023 - IPC G01N33/92 A61B5/00 

FIELD: laboratory diagnostics in physiology and immunology.

SUBSTANCE: invention relates to a method of predicting the risk of adaptation failure in people working in unfavorable climatic conditions of the Arctic. The content of CD3-CD16+ natural killer cells circulating in the blood, the concentration of HDL cholesterol and apoA-I are determined. With simultaneous detection of CD3-CD16+ content more than 0.8×10⁹ cells/l, HDL cholesterol concentrations less than 0.8 mmol/l and apoA-I less than 100 mg/dl a high risk of adaptation failure is predicted.

EFFECT: method makes it possible to identify persons at risk of failure of adaptation mechanisms associated with energy supply in the unfavorable climatic conditions of the Arctic as early as possible (before increasing concentrations of total blood cholesterol and LDL, hypertension and signs of coronary insufficiency).

1 cl, 3 ex