QUINOLINE DERIVATIVES FOR USE IN TREATMENT OR PREVENTION OF CANCER Russian patent published in 2024 - IPC A61K31/47 A61K31/706 A61K31/5377 A61K31/4709 A61P35/00 

Abstract RU 2811417 C2

FIELD: pharmaceuticals.

SUBSTANCE: invention relates to the use of a compound of formula (Ib') or a pharmaceutically acceptable salt thereof for the treatment of cancer selected from gastric cancer, gastrointestinal cancer, colorectal cancer, pancreatic cancer, lung cancer and liver cancer in a patient, wherein the said patient does not have clinically detectable metastases or wherein the said patient has clinically detectable metastases and the said compound of formula (Ib') is not directly directed against metastatic invasion, the said compound being 8-chloro-N-(4-(trifluoromethoxy)phenyl)quinoline-2- amine.

EFFECT: obtaining quinoline derivatives for use in the treatment or prevention of cancer.

6 cl, 3 tbl

Similar patents RU2811417C2

Title Year Author Number
BIOMARKERS AND APPLICATIONS IN TREATING VIRAL INFECTIONS, INFLAMMATIONS OR CANCER 2019
  • Pouletty Philippe
  • Ehrlich Hartmut
  • Scherrer Didier
  • Tazi Jamal
  • Manchon Laurent
RU2820481C2
DRUG DELIVERY SYSTEMS BASED ON MAYTANSINOID 2018
  • Kratz, Felix
  • Abu Ajaj, Khalid
  • Warnecke, Anna
  • Nollmann, Friederike I.
  • Koester, Stephan David
  • Garcia Fernandez, Javier
  • Pes, Lara
  • Walter, Heidi-Kristin
  • Magnusson, Johannes Pall
  • Chercheja, Serghei
  • Perez Galan, Patricia
  • Medda, Federico
  • Daum, Steffen Josef
RU2783076C2
COMBINATION THERAPY USING DIARYL MACROCYCLIC COMPOUNDS 2018
  • Cui, Jingrong, Jean
  • Zhai, Dayong
RU2784853C2
METHOD OF TREATING CANCER USING A COMBINATION OF CHK1 AND ATR INHIBITORS 2015
  • Helleday, Thomas
  • Sanjiv, Kumar
RU2736219C2
BENZO[b]THIOPHENE STING AGONISTS FOR TREATMENT OF CANCER 2018
  • Cemerski, Saso
  • Cumming, Jared, N.
  • Kopinja, Johnny, E.
  • Perera, Samanthi, A.
  • Trotter, Benjamin Wesley
  • Tse, Archie Ngai-Chiu
RU2771811C2
BENZIMIDAZOLES USED AS PROTEIN KINASE INHIBITORS 2006
  • Binch Khehjli
  • Mortimor Majkl
  • Robinson Dehniel
  • Stamos Din
  • Ehverit Sajmon
RU2415853C2
ARYLCYCLOPROPYLAMINE BASED DEMETHYLASE INHIBITORS OF LSD1 AND THEIR MEDICAL USE 2011
  • Ortega-Munos Alberto
  • Fajf Mattyu Kolin Tor
  • Martinell-Pedemonte Mark
  • Tirapu-Fernandes-De-La-Kuesta Inigo
  • Estyarte-Martines Mariya-De-Los-Ankheles
RU2611437C2
COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, METHODS FOR PREPARING THE COMPOUNDS AND THEIR USE AS ATR KINASE INHIBITORS 2019
  • Krejn, Sheldon N.
  • Tryuon, Vuj Lin
  • Abdoli, Abbas
  • Tryushon, Zhan-Fransua
  • Blek, Kemeron
  • Dorish, Stefan
  • Fader, Li
  • Lyanua, Stefani
  • Dzhons, Pol
  • Sen-Onzh, Migel
  • Pikar, Odri
  • Lakbej, Sajrus M.
RU2806857C2
PYRAZOLO[3,4-b]PYRIDINE COMPOUNDS AS TAM AND MET KINASE INHIBITORS 2019
  • Hinklin, Ronald Jay
  • Allen, Shelley
  • Barbour, Patrick
  • Cook, Adam
  • Dahlke, Joshua
  • Gaudino, John
  • Laird, Ellen
  • Mcnulty, Oren T.
  • Zhao, Qian
RU2773611C1
REDUCTION OF TUMOR MASS BY INJECTING CCR1 ANTAGONISTS IN COMBINATION WITH PD-1 INHIBITORS OR PD-L1 INHIBITORS 2017
  • Sharo Izrael
  • Chon Khejyun
  • Shall Tomas Dzh.
  • Chzhan Penli
RU2745195C2

RU 2 811 417 C2

Authors

Pouletty Philippe

Ehrlich Hartmut

Scherrer Didier

Tazi Jamal

Dates

2024-01-11Published

2019-12-19Filed