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(19)

(11)

2 771 811

(13)

(51)

IPC

A61K31/381(2006-01-01)

A61K31/385(2006-01-01)

A61K31/424(2006-01-01)

A61P35/00(2006-01-01)

A61P35/02(2006-01-01)

A61P35/04(2006-01-01)

A61P43/00(2006-01-01)

(21) (22)

Application

2020109330, 2018-07-30

(24)

Start date

2018-07-30

(22)

Actual filing date

2018-07-30

(45)

Published

2022-05-12

(72)

Inventor

Cemerski, SasoCumming, Jared, N.Kopinja, Johnny, E.Perera, Samanthi, A.Trotter, Benjamin WesleyTse, Archie Ngai-Chiu

(73)

Holder

Merck Sharp Dohme Corp.

BENZO[b]THIOPHENE STING AGONISTS FOR TREATMENT OF CANCER Russian patent published in 2022 - IPC A61K31/381 A61K31/385 A61K31/424 A61P35/00 A61P35/02 A61P35/04 A61P43/00

Abstract RU 2771811 C2

FIELD: medicine.

SUBSTANCE: invention relates to a method for the treatment of a cell-proliferative disorder, wherein the specified method includes the administration to a subject who needs it of a benzo[b]thiophene STING agonist; where the benzo[b]thiophene STING agonist is administered once every 3-28 days; and the benzo[b]thiophene STING agonist is selected from a group consisting of:

or their pharmaceutically acceptable salt. and

EFFECT: obtaining a method for the treatment of cancer.

8 cl, 2 ex

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RU 2 771 811 C2

Authors

Cemerski, Saso

Cumming, Jared, N.

Kopinja, Johnny, E.

Perera, Samanthi, A.

Trotter, Benjamin Wesley

Tse, Archie Ngai-Chiu

Dates

2022-05-12—Published

2018-07-30—Filed