PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF PERIODONTOSIS OR TRAUMATIC TOOTH DISLOCATION Russian patent published in 2024 - IPC A61K38/08 A61P1/02 C07K7/06 

FIELD: dentistry.

SUBSTANCE: group of inventions concerns various applications of a composition containing a peptide or a pharmaceutically acceptable salt thereof, where the peptide contains the amino acid sequence of the following general formula 1: KYKQ-X5-X6-X7-X8-YK (general formula 1), wherein in general formula 1, X5 to X7 are each independently arginine (R) or lysine (K); X8 is asparagine (N) or serine (S). The following is suggested: the use of a pharmaceutical composition containing the above peptide or a pharmaceutically acceptable salt thereof for the prevention or treatment of traumatic tooth dislocation. It is also proposed to use a composition containing the above peptide for the regeneration of the periodontal ligament. The above peptide has the effect of regenerating alveolar bone and forming new tissue like tooth root cementum tissue and new tissue like periodontal ligament tissue, and the new periodontal ligament formed by the peptide of the present invention is embedded in the newly formed alveolar bone and cementum tooth root.

EFFECT: inventions can be used both for the regeneration of the periodontal ligament and for the prevention or treatment of traumatic tooth dislocation.

12 cl, 5 tbl, 5 ex, 6 dwg